The Sheiner-Rowland Advanced Course in PKPD Sils-Maria 2018

Sunday April 8 through Friday April 13

An advanced course presenting aspects and applications of pharmacokinetics, pharmacodynamics and kinetic/dynamic data analysis in the medical and pharmaceutical sciences.

For whom intended:
The Course is designed for those who have a good working knowledge of basic concepts in pharmacokinetics, pharmacodynamics and data analysis and who now wish to extend their knowledge further. Emphasis will be placed on relating pharmacokinetics to underlying physiological processes and to pharmacodynamics, and on the analysis and modelling of pharmacokinetic and pharmacodynamic data.

Course content: 
The mornings will be devoted to lectures; the late afternoons to small-group workshops led by experienced tutors, in which participants will solve practical problems and develop facility with the techniques and approaches discussed in the lectures. The participants are encouraged to raise questions from their experience for discussion: time is specifically reserved for informal consultations.

Course manual: 
A course manual, comprising lecture outlines, derivations, problem sets with answers, and additional reading material will be provided in an electronic format.

This is not a computer modelling training course. There are no computer exercises. However, participants should come with a scientific hand calculator or notebook computer.

Ability to understand and converse in English is essential.

Registration and Local Details:

http://www.pkworkshops.com/adv-wksp2018.htm

TIMETABLE (Preliminary Version – subject to change)

Sunday 8th April

18:00                           Welcome and pick-up manual

19.00                           Dinner

Monday 9th April

08:45-09:00                Introduction (Leon Aarons)

09:00-10:15                Lecture 1 – Empirical Pharmacokinetics (Leon Aarons)

10:15-10:45                Coffee

10:45-12:00                Lecture 2 – Pharmacodynamic Principles (Steve Duffull)

12:30-14:00                Lunch

15:00-16:00                Consultation (optional)

16:00-19:00                Workshop I – Empirical PK/PD Principles

19:00                           Reception

19:30                           Dinner

 

Tuesday 10th April

09:00-10:15                Lecture 3 – Physiologically Based Pharmacokinetics (Leon Aarons)

10:15-10:45                Coffee

10:45-12:00                Lecture 4 – PKPD Principles (Nick Holford)

12:30-14:00                Lunch

15:00-16:00                Consultation (optional)

16:00-19:00                Workshop II – PBPK/PKPD Principles

19:30                           Dinner

 

Wednesday 11th April

09:00-10:15                Lecture 5 – Nonlinear regression (France Mentre)

10:15-10:45                Coffee

10:45-12:00                Lecture 6 – Population PKPD – Models & methods (Mats Karlsson)

12:30-14:00                Lunch

15:00-16:00                Consultation (optional)

16:00-19:00                Workshop III – Nonlinear regression/Population PK

19:30                           Dinner

 

Thursday 12th April

09:00-10:15                Lecture 7 – Population PKPD – Modelling (Mats Karlsson)

10:15-10:45                Coffee

10:45-12:00                Lecture 8 – Disease Progression Principles (Nick Holford)

12:30-14:00                Lunch

15:00-16:00                Consultation (optional)

16:00-19:00                Workshop IV – Population PKPD/Disease Progression Principles

19:30                           Course Dinner

 

Friday `13th April

09:00-10:15                Lecture 9 – Optimal design (Steve Duffull)

10:15-10:45                Coffee

10:45-12:00                Lecture 10 – Models for discrete and time-to-event data (France Mentre)

12:00                           Lunch

 

END OF COURSE